Computational and Evolutionary Genomics

URL: http://bioinformatics.cs.vt.edu/~zhanglab
Contact: Liqing Zhang

We analyze genomes to infer interesting evolutionary events, with a focus on the divergence of duplicated genes in both primary sequences and function. We develop methods to analyze the human SNPs (single nucleotide polymorphisms) to understand the associations between different genetic diseases. We also develop open source software and online databases for analyzing high throughput data. We are currently developing a program for detecting gene conversion (non-reciprocal transfer of genetic information from one sequence to another) using machine learning approach.